Drug intelligence / Profile preview

secale cereale allergen extract

Development stage
Phase 2
Lead developer
Leti Pharma
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Oral, Subcutaneous, Intradermal
01

Overview

Secale cereale allergen extract is an extract derived from the pollen of rye (Secale cereale). It is utilized for both the diagnosis of rye pollen allergy and for allergen-specific immunotherapy (AIT). For diagnostic purposes, the extract is administered via a skin prick test; a positive wheal-and-flare reaction in a sensitized individual confirms the presence of specific IgE antibodies. [18, 19, 25] As a therapeutic agent, progressively larger doses are given to the patient, typically through subcutaneous injection, to induce immunological tolerance and mitigate allergic symptoms upon environmental exposure to rye pollen. [18] LETI Pharma, the sponsor of the clinical trial referenced in the provided context, is a known developer of allergenic extracts for both diagnostic and therapeutic applications. [22, 23, 26]

Brand names
Depigoid
Other names
Rye pollen allergen extractSecale cereale pollen extractCultivated annual rye pollen
02

Targets

IgE (Immunoglobulin E)

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