Drug intelligence / Profile preview

Sechang Zhixie Powder

Development stage
Phase 4
Lead developer
China Shenwei Pharmaceutical Group
Modality
Small Molecules
Administration
Oral
01

Overview

Sechang Zhixie Powder is a traditional Chinese medicine (TCM) formulation with a long history of use among the Yi people in Yunnan, China for the treatment of pediatric diarrhea. The formula is composed primarily of herbal ingredients such as Rodgersia sambucifolia and other botanicals. It is indicated for acute diarrhea, especially in children with symptoms attributed to spleen and stomach qi deficiency or indigestion. Pharmacological studies have demonstrated antidiarrheal effects in animal models, likely through mechanisms involving modulation of gut microbiota and anti-inflammatory actions[1][2][7]. The product has been developed into a proprietary powder formulation by China Shineway Pharmaceutical Group Limited and is undergoing clinical research as a first-line therapy for pediatric acute diarrhea[6].

Brand names
Sechang Zhixie Powder
Other names
Se Chang Zhi Xie Powder涩肠止泻散Sechang-Zhixie-SanSCZX
02

Targets

EGFR (Epidermal growth factor receptor)SLC10A2 (Solute carrier family 10 member 2)STAT3 (Signal Transducer and Activator of Transcription 3)

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