secretin human

Secretin human is a synthetic version of the endogenous gastrointestinal peptide hormone secretin. In the context of research conducted by Turku University Hospital, it is being investigated for its potential to treat obesity by activating brown adipose tissue (BAT) and inducing satiation. Secretin acts as an agonist at the secretin receptor, which is expressed in various tissues including the pancreas, brain, and brown adipose tissue. By stimulating BAT, secretin increases thermogenesis and glucose uptake, while its action in the central nervous system is thought to signal fullness, thereby reducing food intake. Clinical studies utilize PET/CT and fMRI imaging to monitor metabolic activity in BAT and brain responses to food stimuli following secretin administration.

Other names

secretin hydrochloridehuman secretin