Selactosol

Selactosol is a proprietary **water-solubilized formulation of selamectin** being developed by Mountain Valley MD for infectious disease and veterinary applications using its Quicksol formulation technology. Selamectin is a **small-molecule macrocyclic lactone antiparasitic endectocide** that is believed to act primarily by binding glutamate-gated chloride channels in susceptible invertebrates, increasing chloride conductance and causing parasite neuromuscular paralysis and death; activity against mycobacterium-based infections has been explored preclinically but the precise antibacterial therapeutic mechanism remains less well established than its antiparasitic mechanism. According to the provided context, Selactosol was designed to overcome selamectin's poor aqueous solubility, enabling formulations such as aqueous solution, topical cream, rapid-dissolve sublingual dosage forms, injectable products, and aerosol or pulmonary delivery, with development interest in tuberculosis, Buruli ulcer, leprosy, and parasitic infestations in animals.

Brand names

Selactosol

Other names

water-solubilized selamectinselamectin Quicksol formulation