Drug intelligence / Profile preview

selenious acid + zinc sulfate + cupric sulfate + manganese sulfate

Development stage
Approved
Lead developer
American Regent
Modality
Small Molecules
Administration
Intravenous
01

Overview

**Tralement** is a sterile intravenous parenteral-nutrition additive containing selenious acid, zinc sulfate, cupric sulfate, and manganese sulfate. It is approved for adult and pediatric patients weighing at least 10 kg as a source of selenium, zinc, copper, and manganese when oral or enteral nutrition is not possible, insufficient, or contraindicated. Each mL supplies zinc 3 mg, copper 0.3 mg, manganese 55 mcg, and selenium 60 mcg. The product replenishes essential trace elements required for diverse enzymatic and metabolic functions, including zinc-dependent enzymes, copper- and manganese-dependent antioxidant enzymes, and selenium-containing proteins. It must be diluted in a parenteral-nutrition admixture and is not intended for direct intravenous infusion. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=a49ffb90-f307-433e-a86e-aaea6d6a9982))

Brand names
Tralement
Other names
trace elements injection 4

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