Drug intelligence / Profile preview

senna + docusate sodium + bisacodyl + magnesium hydroxide + polyethylene glycol 3350

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Rectal
01

Overview

This is a combination therapy consisting of five active ingredients commonly used as laxatives for the treatment of constipation and bowel preparation. The components are: - **Senna**: A stimulant laxative that increases peristalsis by direct action on the intestinal mucosa or nerve plexus. - **Docusate sodium**: A stool softener that lowers the surface tension of stool, allowing water and fats to penetrate and soften it. - **Bisacodyl**: Another stimulant laxative that acts directly on the colon to stimulate bowel movements. - **Magnesium hydroxide**: An osmotic laxative that draws water into the intestines, increasing stool bulk and triggering peristalsis. - **Polyethylene glycol 3350 (Miralax)**: An osmotic agent that retains water in the stool, resulting in softer stools and increased frequency of bowel movements[1][2][5][6][8].

Other names
Shriners Hospitals for Children Bowel ProtocolStandard institutional bowel protocol
02

Targets

AQP3 (Aquaporin-3 channel protein)ESR1 (ERα)

Beyond the preview

Go deeper on senna + docusate sodium + bisacodyl + magnesium hydroxide + polyethylene glycol 3350.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on senna + docusate sodium + bisacodyl + magnesium hydroxide + polyethylene glycol 3350.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call