senna + docusate sodium + bisacodyl + magnesium hydroxide + polyethylene glycol 3350

This is a combination therapy consisting of five active ingredients commonly used as laxatives for the treatment of constipation and bowel preparation. The components are: - **Senna**: A stimulant laxative that increases peristalsis by direct action on the intestinal mucosa or nerve plexus. - **Docusate sodium**: A stool softener that lowers the surface tension of stool, allowing water and fats to penetrate and soften it. - **Bisacodyl**: Another stimulant laxative that acts directly on the colon to stimulate bowel movements. - **Magnesium hydroxide**: An osmotic laxative that draws water into the intestines, increasing stool bulk and triggering peristalsis. - **Polyethylene glycol 3350 (Miralax)**: An osmotic agent that retains water in the stool, resulting in softer stools and increased frequency of bowel movements[1][2][5][6][8].

Brand names

Miralax

Other names

senna + docusate sodium + bisacodyl + magnesium hydroxide + Miralax-Shriners Hospitals for Children-opioid-induced constipationShriners Hospitals for Children Bowel ProtocolStandard institutional bowel protocol