Drug intelligence / Profile preview

senna + lactulose

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Senna + lactulose is a combination of two laxatives that work through different mechanisms to treat constipation. Lactulose is an osmotic laxative that draws water into the intestines from surrounding body tissues, thereby softening stools and increasing their volume to stimulate bowel movement. Senna is a stimulant laxative that works by irritating the lining of the intestines, which helps stimulate muscle contractions to facilitate stool passage. This combination may be more effective than either agent alone for treating chronic constipation, particularly in elderly patients.

Brand names
Senokot-S
02

Targets

AQP3 (Aquaporin-3 channel protein)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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