Drug intelligence / Profile preview

Sensicold

Development stage
Phase 3
Lead developer
Docventures
Modality
Small Molecules
Administration
Oral
01

Overview

Sensicold is a fixed-dose combination oral syrup developed and marketed by Docventures Pharmaceuticals for the symptomatic relief of the common cold, influenza, and allergic rhinitis. The formulation contains three active small molecule ingredients: paracetamol (acetaminophen), phenylephrine hydrochloride, and chlorpheniramine maleate. Paracetamol serves as an analgesic and antipyretic by inhibiting prostaglandin synthesis in the central nervous system. Phenylephrine hydrochloride acts as a sympathomimetic nasal decongestant by stimulating alpha-1 adrenergic receptors to induce vasoconstriction in the nasal mucosa. Chlorpheniramine maleate is a first-generation antihistamine that antagonizes H1 receptors to alleviate allergic symptoms such as sneezing, rhinorrhea, and watery eyes. The product is primarily marketed in India for both pediatric and adult use.

Brand names
Sensicold
Other names
Paracetamol + Phenylephrine + Chlorpheniramine syrup
02

Targets

ADRA1A (α1A)HRH1 (Histamine H1 Receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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