Drug intelligence / Profile preview

SentiKin

Development stage
Unknown
Lead developer
Elanco
Modality
Small Molecules
Administration
Oral
01

Overview

**SentiKin** (flupirtine) is a veterinary analgesic developed by Kindred Biosciences for the treatment of post-operative pain in dogs. It is a potassium channel opener that provides non-opioid, non-narcotic pain relief by modulating neuronal excitability without significant anti-inflammatory effects. The drug advanced to a pivotal clinical study in dogs, with pharmacokinetic studies also completed for an extended-release formulation in postoperative pain for cats. Development focused on companion animal health, particularly acute pain management following surgery.[16][17][21]

Brand names
SentiKin
02

Targets

Kir (Inward-rectifier potassium channels)

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