Drug intelligence / Profile preview

Septicol

Development stage
Unknown
Lead developer
Colorado Serum Company
Administration
Injection
01

Overview

Septicol is a veterinary hyperimmune serum developed by Vetal Company for the prevention and treatment of calf septicemia caused by *Escherichia coli*. It provides passive immunization by delivering pre-formed antibodies against specific *E. coli* virulence factors, specifically the K99, F41, and F(Y) pilus (fimbrial) antigens. These antigens are critical for the attachment of enterotoxigenic *E. coli* (ETEC) to the intestinal epithelium of newborn calves. By neutralizing these attachment factors, Septicol prevents bacterial colonization and subsequent systemic infection (septicemia). It is an approved commercial product in the veterinary market, intended for use in newborn calves to provide immediate protection during their most vulnerable period.

Brand names
Septicol
02

Targets

TraA (F-pilin)F5 (Coagulation Factor V)F41 (F41 fimbrial adhesin)

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