serdexmethylphenidate

Serdexmethylphenidate is a prodrug of the central nervous system (CNS) stimulant dexmethylphenidate. It is used in combination with dexmethylphenidate for the treatment of attention deficit hyperactivity disorder (ADHD) in patients aged six years and older. The drug increases extracellular levels of dopamine and norepinephrine in the CNS by blocking their reuptake into presynaptic neurons, leading to altered neurotransmission. Serdexmethylphenidate itself has little or no binding to monoaminergic reuptake transporters; its therapeutic effect is due to its conversion to active dexmethylphenidate[3][5][6]. The combination product provides extended plasma concentrations and therapeutic benefit with once-daily dosing[6].

Brand names

Azstarys

Other names

KP-415 inner saltKP415 inner saltKP 415 inner saltUNII-0H8KZ470DWUNII0H8KZ470DWUNII 0H8KZ470DW1996626-29-9