Drug intelligence / Profile preview

seridopidine

Development stage
Preclinical
Lead developer
Saniona
Modality
Small Molecules
Administration
Oral
01

Overview

Seridopidine is an investigational small‑molecule dopidine-class compound originally developed by NeuroSearch and later acquired by Saniona, evaluated primarily for central nervous system indications such as Huntington’s disease and other movement or psychiatric disorders.[13][18] Dopidines are characterized by a distinct phenotypic profile that includes dopaminergic and serotonergic receptor interactions and potential modulation of motor and behavioral symptoms, and seridopidine is closely related to pridopidine (Huntexil), though detailed receptor pharmacology for seridopidine itself has not been fully disclosed.[11][13][18] Clinical work to date has focused on assessing safety and exploratory efficacy in early-phase trials, and the program has been de‑prioritized relative to other pipeline assets.[13][18]

Other names
seridopidine
02

Targets

SIGMAR1 (Sigma non-opioid intracellular receptor 1)DRD2 (Dopamine D2 Receptor)

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