Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
sermorelin
- Development stage
- Preclinical
- Lead developer
- Merck KGaA
- Modality
- Peptides, Recombinant Proteins and Enzymes
- Administration
- Subcutaneous, Intravenous
01
Overview
Sermorelin is a synthetic peptide analog of growth hormone-releasing hormone (GHRH), specifically comprising the first 29 amino acids of endogenous human GHRH. It acts as a growth hormone secretagogue by binding to the growth hormone-releasing hormone receptor on pituitary somatotrophs, stimulating the release of endogenous growth hormone (GH). This mechanism mimics natural physiological GH secretion patterns and is regulated by negative feedback via somatostatin. Sermorelin was primarily developed for diagnostic evaluation and treatment of children with growth hormone deficiency or failure to thrive due to insufficient endogenous GH production. Unlike exogenous recombinant human GH therapy, sermorelin promotes pulsatile GH release and supports maintenance of pituitary function[1][3][4][5][8].
- Brand names
- GerefGeref Diagnostic
- Other names
- sermorelin acetate
02
Targets
GHRHR (Growth hormone-releasing hormone receptor)
Beyond the preview
Go deeper on sermorelin.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on sermorelin.