sertraline

**Sertraline** is a selective serotonin reuptake inhibitor (*SSRI*) antidepressant used to treat major depressive disorder; obsessive-compulsive disorder; panic disorder; post-traumatic stress disorder; social anxiety disorder; and premenstrual dysphoric disorder. It works primarily by inhibiting the serotonin transporter (*SERT*), increasing levels of serotonin in the brain and thereby improving mood and emotional balance. Secondary pharmacological actions include weak inhibition of the dopamine transporter (*DAT*) at higher doses and antagonism at sigma-1 receptors. The original developer was Pfizer[2][7]. The drug is widely prescribed due to its efficacy and relatively favorable side effect profile compared to older antidepressants[5].

Brand names

ZoloftLustralAbisertActiserAdjuvinAlarm ForteSertagenSertanSertexSertivaSertivanSertraSertracorSertragenSertral (various)SertraletSertralin - 1 A Pharma (and variants)AAA-Pharma (Sertralin AAA-Pharma)Ranbaxy (Sertraline Ranbaxy)RIA Generics (Sertraline RIA)Sandoz (Sertraline Sandoz)Sanis Health (Sertraline Sanis Health)Sivem Pharmaceuticals (Sertraline Sivem)Teva (various forms of Sertraline Teva and related names in different countries)Zentiva (Sertraline Zentiva)Zydus France (Sertraline Zydus France)Dr. Reddy's Laboratories Australia (Sertraline-DRLA/Dr. Reddy's Laboratories Australia)

Other names

(1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride