Drug intelligence / Profile preview

Sevofran

Development stage: Phase 4
Lead developer: Hana Pharmaceuticals
Modality: Small Molecules
Administration: Inhalation

Overview

Sevofran is a generic formulation of the volatile anesthetic sevoflurane, manufactured by Hana Pharmacy in South Korea. It is a small molecule, halogenated ether used for the induction and maintenance of general anesthesia in both adult and pediatric patients. Sevoflurane acts by modulating various ion channels in the central nervous system, primarily enhancing the activity of inhibitory GABA-A and glycine receptors while inhibiting excitatory nicotinic acetylcholine and NMDA receptors. Asan Medical Center conducted a Phase 4 clinical trial to evaluate the efficacy and safety of Sevofran compared to the original branded sevoflurane (Ultane/Sevorane) in patients undergoing elective surgery under general anesthesia.

Brand names: Sevofran
Other names: generic sevoflurane

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)GABRR (GABA-A receptor subunit rho)Glycine receptor

Beyond the preview

Go deeper on Sevofran.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Sevofran.

Explore the full profile