Drug intelligence / Profile preview

SF-MSC-EX

Development stage
Phase 2
Lead developer
Eskişehir Osmangazi University
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intraarticular
01

Overview

SF-MSC-EX is an autologous exosome-based therapy derived from mesenchymal stem cells (MSCs) isolated from synovial fluid. Developed by researchers at Eskişehir Osmangazi University, the therapy is designed to treat degenerative meniscal injuries by leveraging the regenerative and anti-inflammatory properties of MSC-derived extracellular vesicles. These exosomes contain a cargo of proteins, lipids, and nucleic acids that facilitate paracrine signaling to promote tissue repair and modulate the microenvironment within the knee joint. The treatment is administered via intra-articular injection and is being compared to the administration of the source synovial fluid-derived mesenchymal stem cells themselves in clinical trials.

Other names
autologous synovial fluid mesenchymal stem cell-derived exosomessynovial fluid-derived mesenchymal stem cell-derived exosomes

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