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SFR-9216
- Development stage
- Unknown
- Lead developer
- Tianjin Puying Biotechnology
- Modality
- Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
- Administration
- Parenteral
01
Overview
SFR-9216 is an investigational recombinant human serum albumin/interferon alfa-2b fusion protein developed for chronic hepatitis B. The interferon alfa-2b component is expected to activate the type I interferon receptor complex, comprising interferon alpha/beta receptor 1 and interferon alpha/beta receptor 2, to induce antiviral interferon-stimulated gene programs through JAK-STAT signaling. Public Chinese trial records identify Phase 1 studies in healthy volunteers and patients with chronic hepatitis B; no marketing approval or assigned INN was identified. ([synapse.patsnap.com](https://synapse.patsnap.com/drug/abc94969a7e04b2488e98704db4206da))
- Other names
- albumin/interferon alfa-2brecombinant human serum albumin/interferon alfa-2b fusion protein
02
Targets
IFNAR2 (Interferon alpha/beta receptor subunit 2)IFNAR1 (Interferon alpha/beta receptor 1)
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