Drug intelligence / Profile preview

SG-9

Development stage
Preclinical
Lead developer
Delhi University
01

Overview

SG-9: sourced facts only. name: "Therefore, novel carbazole derivatives SG-9 and SG-10 proved to be effective inhibitors of mutant hSOD1 protein aggregation and can be further utilised as lead molecules for the amelioration of mutant hSOD1 aggregation-associated ALS." [PMID:39914221]; target: "Therefore, novel carbazole derivatives SG-9 and SG-10 proved to be effective inhibitors of mutant hSOD1 protein aggregation and can be further utilised as lead molecules for the amelioration of mutant hSOD1 aggregation-associated ALS." [PMID:39914221]; developer: "Dr. B. R. Ambedkar Centre for Biomedical Research, University of Delhi, New Delhi 110007 India." [PMID:39914221]; stage: "Molecules SG-9 and SG-10 did not display toxicity and prevented Neuro-2a cells expressing hSOD1 G85R protein from its associated cytotoxicity." [PMID:39914221]

02

Targets

Misfolded SOD1

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