sh-Polypeptide-9

sh-Polypeptide-9, also known as CG-VEGF or Vascular Endothelial Growth Factor Substitute Peptide, is a synthetic recombinant biomimetic peptide designed to replicate the biological activity of endogenous vascular endothelial growth factor (VEGF). Developed primarily by Caregen, this peptide acts as an agonist for VEGF receptors, particularly VEGFR-2, thereby stimulating angiogenesis, promoting microcirculation, and enhancing the delivery of nutrients to tissues such as hair follicles and skin cells. It is widely utilized in aesthetic medicine and dermatology, specifically in injectable hair fillers (e.g., Dr. CYJ Hair Filler) and topical treatments for androgenetic alopecia and skin rejuvenation. By activating the VEGF signaling pathway, it encourages the proliferation of endothelial cells and dermal papilla cells, supporting the growth phase of the hair cycle and improving tissue repair and vascularization.

Brand names

CG-VEGF

Other names

Vascular Endothelial Growth Factor Substitute PeptideVEGF-mimetic peptideRecombinant Human Vascular Endothelial Growth Factor Substitute Peptide