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Shandong Provincial Hospital Affiliated to Shandong First Medical Univ. FLT3 compound 6h
- Development stage
- Unknown
- Lead developer
- Shandong Provincial Hospital Affiliated to Shandong First Medical University
01
Overview
Shandong Provincial Hospital Affiliated to Shandong First Medical Univ. FLT3 compound 6h: sourced facts only. name: "Notably, the preliminary kinase selectivity results showed 6h displayed selectivity for FLT3 kinase (IC50 = 58.6 nM) over other kinases screened, including the homologous c-KIT." [PMID:42571759]; target: "Notably, the preliminary kinase selectivity results showed 6h displayed selectivity for FLT3 kinase (IC50 = 58.6 nM) over other kinases screened, including the homologous c-KIT." [PMID:42571759]; developer: "Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250012, China." [PMID:42571759]; stage: "Furthermore, in a MOLM-13 xenograft model, 6h at the dosage of 30 mg/kg exhibited effective antitumor activity without notable body-weight loss and the major organ damage." [PMID:42571759]
02
Targets
FLT3 (Fms related receptor tyrosine kinase 3)
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