Shandong Univ. HDAC8 compound 11k

Shandong Univ. HDAC8 compound 11k: sourced facts only. name: "Among them, the tetrahydroquinoline derivative 11k exhibited potent HDAC8 inhibitory activity (IC50 = 0.10 μM), and the indole derivative 5b also showed activity (IC50 = 0.28 μM), both with excellent selectivity." [PMID:41785528]; target: "Among them, the tetrahydroquinoline derivative 11k exhibited potent HDAC8 inhibitory activity (IC50 = 0.10 μM), and the indole derivative 5b also showed activity (IC50 = 0.28 μM), both with excellent selectivity." [PMID:41785528]; developer: "Department of Medicinal Chemistry, State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shandong Key Laboratory of Druggability Optimization and Evaluation for Lead Compounds, Shandong Basic Science Academic Special Zone/ Research Center (Pharmacy), School of Pharmaceutical Sciences, Cheelo College of Medicine, Shandong University, Jinan, Shandong, PR China." [PMID:41785528]