Drug intelligence / Profile preview

Shandong Univ. HPSE compound 28

Development stage
Unknown
Lead developer
Shandong University
01

Overview

Shandong Univ. HPSE compound 28: sourced facts only. name: "A 3-O-sulfated HS nonasaccharide 28 exhibited sub-micromolar HPSE inhibitory potency (IC50 = 0.761 μM) and is expected to minimize anticoagulant liabilities by lacking the canonical antithrombin-binding sequence." [PMID:42574901]; target: "A 3-O-sulfated HS nonasaccharide 28 exhibited sub-micromolar HPSE inhibitory potency (IC50 = 0.761 μM) and is expected to minimize anticoagulant liabilities by lacking the canonical antithrombin-binding sequence." [PMID:42574901]; developer: "State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, Shandong, China." [PMID:42574901]

02

Targets

HPSE (Heparanase)

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