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Shanghai Jenomed Biotech personalized cancer vaccine
- Development stage
- Preclinical
- Lead developer
- Shanghai Jenomed Biotech
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Injection
01
Overview
Shanghai Jenomed Biotech is developing a preclinical-stage personalized cancer vaccine (PCV) platform. The technology involves identifying tumor-specific neoantigens from circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) using whole exome sequencing (WES) and RNA sequencing (RNA-seq). These identified neoantigens are then incorporated into a customized vaccine designed to stimulate a patient-specific anti-tumor immune response. Preclinical studies in mouse models have demonstrated the platform's potential in treating lung cancer, skin cancer, and liver cancer.
- Other names
- PCVpersonalized cancer vaccineneoantigen vaccine
02
Targets
pMHC-I (Peptide–MHC class I complex)
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