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Shanhaidan Granules
- Development stage
- Unknown
- Lead developer
- Longhua Hospital Shanghai University of Traditional Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Shanhaidan Granules is a Traditional Chinese Medicine (TCM) formulation developed by LongHua Hospital, affiliated with the Shanghai University of Traditional Chinese Medicine, specifically for the treatment of hypertension, particularly in patients presenting with the blood stasis pattern. The preparation is a complex mixture of herbal extracts, typically including *Salvia miltiorrhiza* (Danshen), *Panax notoginseng* (Sanqi), and *Ligusticum chuanxiong*. Its mechanism of action involves improving vascular endothelial function by increasing nitric oxide production, inhibiting the renin-angiotensin-aldosterone system, and reducing blood viscosity through anti-platelet effects. It is primarily used as a hospital preparation and has been evaluated in clinical trials for its efficacy in lowering blood pressure and improving cardiovascular hemodynamics.
- Brand names
- Shanhaidan
- Other names
- Shanhaidan KeliShan Hai Dan Granules
02
Targets
NOS1 (nNOS)ACE (Angiotensin Converting Enzyme)
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