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Shaofu Zhuyu Formula (also known as Shaofuzhuyu Decoction or Shaofu Zhuyu Tang) is a classic Traditional Chinese Medicine (TCM) herbal formulation first described by Wang Qingren in the 19th-century text *Yi Lin Gai Cuo*. It is specifically designed to treat gynecological and abdominal disorders characterized by "blood stasis" and "internal cold." The formula typically comprises ten botanical and animal-derived ingredients, including *Angelica sinensis* (Dang Gui), *Pollen Typhae* (Pu Huang), *Faeces Trogopterori* (Wu Ling Zhi), *Corydalis yanhusuo* (Yan Hu Suo), *Cinnamomum cassia* (Rou Gui), *Ligusticum chuanxiong* (Chuan Xiong), *Paeonia lactiflora* (Chi Shao), *Commiphora myrrha* (Mo Yao), *Foeniculum vulgare* (Xiao Hui Xiang), and *Zingiber officinale* (Gan Jiang). Pharmacologically, it is recognized for its analgesic, anti-inflammatory, and hemorheological properties, which help to improve pelvic blood flow and regulate uterine contractions. It is currently being evaluated in clinical trials for the treatment of primary dysmenorrhea, female infertility associated with uterine cold, and recurrent spontaneous abortion.
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