Drug intelligence / Profile preview

Shaoyao Shujing

Development stage
Unknown
Lead developer
Guangdong Provincial Hospital of Traditional Chinese Medicine
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Shaoyao Shujing is a Traditional Chinese Medicine (TCM) herbal preparation developed by the Guangdong Provincial Hospital of Chinese Medicine, specifically formulated as a tablet for the treatment of knee osteoarthritis. The name "Shaoyao" refers to the primary ingredient, *Paeonia lactiflora* (Peony), which is traditionally used in Chinese medicine for its analgesic, anti-inflammatory, and antispasmodic properties. "Shujing" translates to "relaxing the tendons," reflecting its clinical use in alleviating joint stiffness and pain. The drug has been evaluated in clinical trials using magnetic resonance imaging (MRI) to assess its impact on joint structure and symptom relief in patients with early-stage knee osteoarthritis. It is typically classified as a hospital preparation (医院制剂) in China.

Other names
Shaoyao Shujing tabletShaoyao Shujing pian
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)HSD11B2 (11β-HSD2)ESR2 (ERβ)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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