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Shehuang

Development stage: Unknown
Lead developer: Chengdu University of Traditional Chinese Medicine
Administration: Topical

Overview

Shehuang is a topical Traditional Chinese Medicine (TCM) formulation developed by Chengdu Huasen Pharmaceutical High-Tech for the treatment of chronic eczema. The preparation, often referred to as Shehuang Cream or Shehuang Rugao, typically incorporates active components such as artificial musk and sulfur, which are recognized in traditional medicine for their anti-inflammatory, antipruritic, and antiseptic properties. It has been investigated in Phase II clinical trials in China (e.g., CTR20132696) to evaluate its efficacy and safety profile compared to placebo in patients suffering from chronic eczema.

Brand names: Shehuang
Other names: Shehuang creamShehuang rugao

Targets

TRPM8 (Transient receptor potential cation channel subfamily M member 8)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)GR (Glucocorticoid receptor)

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