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Shen Ling Gu Ben immune granules is a Traditional Chinese Medicine (TCM) formulation developed by the China Academy of Chinese Medical Sciences. It is primarily investigated as an adjunctive therapy for HIV/AIDS patients who exhibit an inadequate immune response (poor CD4+ T-cell recovery) despite receiving stable combined antiretroviral therapy (cART/HAART). The formulation is designed to strengthen the spleen and consolidate the root (Shen Ling Gu Ben), a concept in TCM aimed at enhancing the body's immune function and overall constitution. Clinical studies, such as ChiCTR1800015290, evaluate its efficacy in promoting immune reconstitution and reducing chronic inflammation in HIV-infected individuals.
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