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Shen No. 9 Recipe (SR) is a multi-component traditional Chinese medicine (TCM) herbal formula investigated for the treatment of idiopathic membranous nephropathy (IMN), particularly in patients who are refractory to or have not responded to conventional Western therapies such as corticosteroids or immunosuppressive agents. The formula is typically administered orally and has been studied in combination with other TCM preparations like Qingre Moshen Granule (QMG). Its mechanism of action is characterized by immunomodulatory activity, specifically through the regulation of cellular immune function and the modulation of cytokine levels, including interleukin-2 (IL-2). Clinical research indicates that the recipe may help reduce proteinuria and improve renal function in patients with chronic kidney disease associated with IMN.
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