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Shenan decoction

Development stage: Preclinical
Lead developer: Hospital Affiliated to Changchun University of Traditional Chinese Medicine
Administration: Oral

Overview

Shenan decoction is a traditional Chinese medicine (TCM) formulation currently undergoing clinical investigation for the treatment of Diabetic Nephropathy (also known as Diabetic Kidney Disease). It is being studied for its potential to improve renal function, reduce microinflammatory states, and enhance insulin sensitivity in patients with early-stage Diabetic Kidney Disease. The decoction is developed by institutions like the Affiliated Hospital of Changchun University of Chinese Medicine and Changchun University of Chinese Medicine, with support from national research programs in China.

Targets

PIK3CA (Phosphoinositide 3-kinase alpha)STAT3 (Signal Transducer and Activator of Transcription 3)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)EGFR T790M (Epidermal growth factor receptor T790M mutant)

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