Drug intelligence / Profile preview

Shenfu Xiangshao Decoction

Development stage
Preclinical
Administration
Oral
01

Overview

Shenfu Xiangshao Decoction is a traditional Chinese medicine (TCM) herbal formula used primarily for the treatment of heart failure and to improve quality of life and activity tolerance in affected patients. It is based on the classical Shenfu decoction, which typically contains Panax ginseng (Asian ginseng) and Aconitum carmichaeli (processed aconite), but "Xiangshao" indicates a modified or extended formulation, though specific additional ingredients are not detailed in available sources. The mechanism of action is believed to involve enhancement of cardiac contractility, improvement of coronary blood supply, protection against myocardial ischemia, reduction of inflammatory mediators such as tumor necrosis factor-α (TNF-α), scavenging free radicals, and modulation of neurohormonal factors like angiotensin converting enzyme (ACE), renin (REN), aldosterone (ALD), atrial natriuretic polypeptide (ANP), among others[1][3][9]. Clinical studies suggest it may improve left ventricular ejection fraction and hepatic function in chronic heart failure patients[1][9].

Brand names
Shenfu Xiangshao Decoction
Other names
参附香芍汤
02

Targets

ACE (Angiotensin Converting Enzyme)MR (Mineralocorticoid receptor)MAPK14 (p38 mitogen-activated protein kinase alpha)REN (Renin)TNFA (Tumor necrosis factor alpha (soluble))NPPA (Atrial natriuretic peptide precursor)

Beyond the preview

Go deeper on Shenfu Xiangshao Decoction.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Shenfu Xiangshao Decoction.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call