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Shenfu Xiaozheng Decoction
- Development stage
- Unknown
- Lead developer
- Hangzhou Hospital of Traditional Chinese Medicine
- Administration
- Oral, Intravenous
01
Overview
Shenfu Xiaozheng Decoction is a Traditional Chinese Medicine (TCM) herbal formula being investigated for the treatment of autosomal dominant polycystic kidney disease (ADPKD). The decoction is formulated based on TCM principles to 'tonify the kidney and resolve stasis,' specifically targeting the pathogenesis of renal cyst formation and enlargement. It typically incorporates core herbs such as Ginseng and Aconite to support vital energy (Qi), alongside 'Xiaozheng' herbs intended to eliminate masses or cysts. In clinical research, it is often evaluated as an adjunctive therapy to vasopressin V2 receptor antagonists like tolvaptan to enhance therapeutic efficacy, reduce total kidney volume growth, and potentially mitigate the side effects of Western pharmacological treatments.
- Other names
- Shenfu Xiaozheng Tang
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