Drug intelligence / Profile preview

shengdi dahuang decoction

Development stage
Phase 4
Administration
Oral
01

Overview

Shengdi Dahuang Decoction is a traditional Chinese medicine (TCM) herbal formula historically used as a hemostatic agent and for the treatment of acute hemorrhagic conditions such as intracerebral hemorrhage. The formula typically contains Rehmanniae Radix (Sheng Di Huang) and Rhei Radix et Rhizoma (Da Huang). Preclinical studies indicate that it exerts anti-inflammatory effects by inhibiting microglial activation and downregulating inflammatory mediators such as TLR4, NF-κB, TNF-α, and IL-1β in models of intracerebral hemorrhage. This leads to improved neurological function and reduced brain edema in animal models[1][2]. Its precise mechanism remains under investigation but is thought to involve modulation of neuroinflammation. It is used primarily within the context of complementary or alternative medicine for acute stroke management[3].

Brand names
shengdi dahuang decoction
Other names
Sheng-Di-Da-Huang Decoction生地大黄汤
02

Targets

NF-κBTLR4 (Toll-like receptor 4)

Beyond the preview

Go deeper on shengdi dahuang decoction.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on shengdi dahuang decoction.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call