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Shengji Huahua Granules
- Development stage
- Unknown
- Lead developer
- Wanbangde Pharmaceutical Group
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Shengji Huahua Granules (also known as Xinshenghua Keli or Xin Sheng Hua Granules) is an approved traditional Chinese medicine (TCM) formulation developed and marketed by Wanbangde Pharmaceutical Group. Formulated as oral granules, it is primarily indicated for gynecological conditions to promote blood circulation, resolve blood stasis, and alleviate pain. It is commonly used to treat postpartum lochiometra (postpartum retention of lochia) and abdominal pain, and can also be used for vaginal bleeding or menorrhagia caused by intrauterine device (IUD) insertion. The formulation consists of several active herbal ingredients, including *Angelica sinensis* (Danggui), *Leonurus japonicus* (Yimucao), *Ligusticum chuanxiong* (Chuanxiong), *Prunus persica* (Taoren), *Carthamus tinctorius* (Honghua), *Glycyrrhiza uralensis* (Zhigancao), and *Zingiber officinale* (Ganjiang).
- Other names
- Shengji Huayu GranulesXin Sheng Hua GranulesXinshenghua Keli新生化颗粒生肌化瘀颗粒
02
Targets
EGFR (Epidermal growth factor receptor)ITGA6 (Integrin alpha-6)NOS2 (Nitric Oxide Synthase 2)NOS3 (eNOS)ODC1 (Ornithine decarboxylase)PLA2G2A (Secretory phospholipase A2 group IIA)PPARG (Peroxisome proliferator-activated receptor gamma)THBS1 (Thrombospondin-1)VEGFA (Vascular endothelial growth factor A)
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