Drug intelligence / Profile preview

Shengmai Liquid

Development stage
Phase 4
Lead developer
Jilin Aodong Pharmaceutical Group
Administration
Oral
01

Overview

Shengmai Liquid is an **oral liquid formulation** of a classic Traditional Chinese Medicine compound, historically known as Shengmai San. It is composed of three primary herbal ingredients: **Codonopsis pilosula**, **Ophiopogon japonicus**, and **Schisandra chinensis**[1][3][10]. Shengmai Liquid is used clinically for cardiovascular support, fatigue, and, more recently, for post-viral fatigue syndromes such as Long COVID fatigue[1][3][10]. Its mechanism of action is thought to involve **improving cardiac contractility**, likely via enhancement of calcium signaling in myocardial cells (including effects on L-type Ca(2+) channels, SR Ca(2+)-ATPase, and ryanodine receptors)[10]. The preparation is recognized for replenishing "Qi" and fluids, nourishing Yin, and supporting the function of the heart in the context of Traditional Chinese Medicine (TCM)[4][8][10].

Brand names
Shengmai LiquidShengmai Yin Oral LiquidShengmaiyin Oral Liquid
Other names
Sheng Mai YinSheng Mai Yin Oral LiquidShengmai San (liquid form)Sheng-Mai-YinSMY
02

Targets

ATP2A (Sarcoplasmic reticulum Ca2+-ATPase)LTCC (Voltage-gated calcium channel (L-type))RYR2 (Ryanodine receptor 2)

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