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shengyang yiwei granules
- Development stage
- Unknown
- Lead developer
- Beijing Tong Ren Tang
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Shengyang Yiwei Chongji (升阳益胃冲剂) is a Traditional Chinese Medicine (TCM) formula originally described by the physician Li Dongyuan in the 'Pi Wei Lun' (Treatise on the Spleen and Stomach) during the Jin-Yuan dynasties. It is a complex herbal combination consisting of 14 ingredients, including Astragalus, Ginseng, and Atractylodes, designed to tonify the spleen, benefit the stomach, and clear damp-heat. The formula is primarily indicated for spleen and stomach qi deficiency accompanied by dampness, manifesting as fatigue, poor appetite, loose stools, and a heavy sensation in the limbs. In modern clinical practice, it is widely used in China for the treatment of chronic gastritis, functional dyspepsia, and chronic fatigue syndrome where the underlying TCM pattern matches spleen deficiency with damp-heat.
- Brand names
- Shengyang Yiwei ChongjiShengyang Yiwei Keli
- Other names
- Shengyang Yiwei Tang升阳益胃冲剂升阳益胃颗粒
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))AMPK (Adenosine monophosphate–activated protein kinase)IL-6 (Interleukin 6)
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