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shenhuang san
- Development stage
- Unknown
- Lead developer
- Jiangsu Provincial Hospital of Traditional Chinese Medicine
- Administration
- Topical, Oral
01
Overview
Shenhuang San is a Traditional Chinese Medicine (TCM) formulation primarily composed of *Panax ginseng* (Ginseng) and *Rheum palmatum* (Rhubarb). It is widely utilized in clinical practice in China, particularly as a hospital-made preparation, for the management of postoperative gastrointestinal dysfunction and intestinal obstruction. The formula is frequently administered as a topical paste applied to the umbilical region (Shenque point) to stimulate bowel movements and promote the recovery of gastrointestinal motility. In the field of oncology, Shenhuang San is investigated for its potential to enhance immune function and improve the quality of life in patients undergoing chemotherapy for gastrointestinal malignancies, such as gastric and colorectal cancers. Its pharmacological effects are attributed to the synergistic action of ginsenosides and anthraquinones, which modulate enteric nervous system activity and systemic inflammatory responses.
- Other names
- 参黄散Shen-Huang-San
02
Targets
AQP3 (Aquaporin-3 channel protein)mAChR (Muscarinic acetylcholine receptors)TNFA (Tumor necrosis factor alpha (soluble))
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