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shenlian granules
- Development stage
- Unknown
- Lead developer
- Guang'anmen Hospital
- Administration
- Oral
01
Overview
Shenlian Granules is a traditional Chinese medicine (TCM) compound formulation primarily composed of extracts from *Panax ginseng* (Ginseng) and *Coptis chinensis* (Huanglian). It is specifically developed for the treatment of type 2 diabetes mellitus (T2DM) and metabolic syndrome. The drug's therapeutic effect is attributed to its ability to improve insulin sensitivity, activate the AMP-activated protein kinase (AMPK) signaling pathway, and reduce systemic chronic inflammation. Clinical research, particularly led by Guang'anmen Hospital of the China Academy of Chinese Medical Sciences, has demonstrated its efficacy in lowering glycated hemoglobin (HbA1c) levels and improving glucose tolerance in patients with insulin resistance. It is often utilized as a hospital preparation in China for metabolic disorders.
- Brand names
- Shenlian Granules参连颗粒
- Other names
- Shen-Lian GranulesShenlian Fang
02
Targets
AMPK (Adenosine monophosphate–activated protein kinase)INSR (Insulin receptor)
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