Drug intelligence / Profile preview

shenma yizhi decoction

Development stage
Unknown
Lead developer
Xiyuan Hospital
Administration
Oral
01

Overview

Shenma Yizhi Decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by Xiyuan Hospital of the China Academy of Traditional Chinese Medicine. It is primarily investigated for the treatment of vascular dementia (VD), specifically targeting patients diagnosed with the TCM syndrome of deficiency, blood stasis, and liver-yang deficiency. The decoction is intended to improve cognitive function and address neurological defects. As a complex herbal mixture, its pharmacological profile likely involves synergistic effects such as enhancing cerebral blood flow, reducing oxidative stress, and providing neuroprotection, although specific molecular targets have not been definitively characterized in clinical trials.

Other names
Shenma Yizhi Tang
02

Targets

M1 (Muscarinic acetylcholine receptor M1)AcetylcholinesteraseCHAT (Choline acetyltransferase)

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