Drug intelligence / Profile preview

Shenqi Detoxification Granule

Development stage: Unknown
Modality: Small Molecules
Administration: Oral

Overview

Shenqi Detoxification Granule (SDG) is a traditional Chinese herbal formula used for the treatment of chronic renal failure. It works by inhibiting progressive fibrosis, a key pathological process in chronic renal disease. Its mechanism involves reducing the expression of connective tissue growth factor (CTGF) and platelet-derived growth factor-B (PDGF-B), which play important roles in extracellular matrix abnormal accumulation. Additionally, it improves nitric oxide (NO) levels and reduces endothelin-1 (ET-1) levels, thereby improving endothelial function and mitigating their roles in mediating renal fibrosis. The formula comprises 12 Chinese herbs, including Radix Astragali (Huang Qi), Salvia miltiorrhiza (Dan Shen), and Angelica sinensis (Dang Gui).

Other names: Shenqi

Targets

PDGFB (PDGF-B)CTGF (Connective tissue growth factor)NO2- (Nitrite)ET-1 (Endothelin-1)

Beyond the preview

Go deeper on Shenqi Detoxification Granule.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Shenqi Detoxification Granule.

Explore the full profile