Drug intelligence / Profile preview

Shenyang Pharma Univ. ALK compound 12k

Development stage
Unknown
Lead developer
Shenyang Pharmaceutical University
01

Overview

Shenyang Pharma Univ. ALK compound 12k: sourced facts only. name: "Among them, 12k bearing 4‑hydroxypiperidinyl group exhibited the optimal activities against tested cells with IC50 values of 51 nM and 175 nM, as well as promising inhibitory effects on ALKWT (3.7 nM) and ALKL1196M (6.8 nM)." [PMID:36113668]; target: "Among them, 12k bearing 4‑hydroxypiperidinyl group exhibited the optimal activities against tested cells with IC50 values of 51 nM and 175 nM, as well as promising inhibitory effects on ALKWT (3.7 nM) and ALKL1196M (6.8 nM)." [PMID:36113668]; developer: "Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China." [PMID:36113668]

02

Targets

ALK (Anaplastic lymphoma kinase receptor tyrosine kinase)

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