Drug intelligence / Profile preview

Shenyang Pharma Univ. EZH2 compound N16

Development stage
Unknown
Lead developer
Shenyang Pharmaceutical University
01

Overview

Shenyang Pharma Univ. EZH2 compound N16: sourced facts only. name: "Compound N16 demonstrates significant inhibitory effects on EZH2 WT, with an IC50 of 0.3 nM." [PMID:41529460]; target: "Compound N16 demonstrates significant inhibitory effects on EZH2 WT, with an IC50 of 0.3 nM." [PMID:41529460]; developer: "School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China." [PMID:41529460]; stage: "Furthermore, compound N16 effectively inhibited the proliferation of Pfeiffer cells (IC50 = 0.0074 ± 0.002 μM) and demonstrated greater efficacy compared to Tazemetostat." [PMID:41529460]

02

Targets

EZH2 (Histone-lysine N-methyltransferase EZH2)

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