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Shenyang Pharma Univ. Mcl-1 compound 47
- Development stage
- Preclinical
- Lead developer
- Shenyang Pharmaceutical University
01
Overview
Shenyang Pharma Univ. Mcl-1 compound 47: sourced facts only. name: "Collectively, 47 represents a novel Mcl-1 inhibitor targeting the P1-P3 pockets with excellent antileukemia effects." [PMID:39121336]; target: "Collectively, 47 represents a novel Mcl-1 inhibitor targeting the P1-P3 pockets with excellent antileukemia effects." [PMID:39121336]; developer: "Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China." [PMID:39121336]; stage: "47 inhibited tumor growth in HL-60 and THP-1 xenograft models with growth inhibition rate of 63.7% and 57.4%, respectively." [PMID:39121336]
02
Targets
MCL1 (Myeloid cell leukemia sequence 1)
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