Drug intelligence / Profile preview

Shenyang Pharma Univ. SHP2 compound 14i

Development stage
Unknown
Lead developer
Shenyang Pharmaceutical University
01

Overview

Shenyang Pharma Univ. SHP2 compound 14i: sourced facts only. name: "The screening result revealed that 14i could exhibit high enzymatic activity against full-length SHP2 (IC50 = 0.104 μM), while showing low inhibitory effect on SHP2-PTP (IC50 > 50 μM)." [PMID:39067422]; target: "The screening result revealed that 14i could exhibit high enzymatic activity against full-length SHP2 (IC50 = 0.104 μM), while showing low inhibitory effect on SHP2-PTP (IC50 > 50 μM)." [PMID:39067422]; developer: "School of Pharmaceutical Engineering, and Key Laboratory of Structure-Based Drug Design & Discovery (Ministry of Education), Shenyang Pharmaceutical University, Shenyang 110016, PR China." [PMID:39067422]

02

Targets

PTPN11 (Tyrosine-protein phosphatase non-receptor type 11)

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