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shenzhiling
- Development stage
- Phase 4
- Lead developer
- Shandong Wohua Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Shenzhiling (SZL) is a Traditional Chinese Medicine (TCM) compound formulation approved in China for the treatment of mild to moderate Alzheimer's disease. It is an oral liquid composed of multiple herbal ingredients and has demonstrated efficacy in improving cognitive function and behavioral symptoms associated with Alzheimer's disease. Preclinical studies indicate that its mechanism involves promoting myelin repair and reducing β-amyloid plaque deposition, potentially through modulation of the PI3K/Akt-mTOR signaling pathway. Clinical research suggests it may delay progression of behavioral and psychological symptoms in Alzheimer's patients[1][2][3][4][5].
- Brand names
- Shenzhiling oral solutionShenZhiLing oral liquid
- Other names
- Shen Zhi LingSZL
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)
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