Drug intelligence / Profile preview

Shi-Xiao-San

Development stage: Unknown
Lead developer: Longhua Hospital Shanghai University of Traditional Chinese Medicine
Administration: Oral

Overview

Shi-Xiao-San is a classic traditional Chinese medicine (TCM) formula, also known as Sudden Smile Powder, primarily composed of Pollen Typhae (Pu Huang) and Faeces Trogopterori (Wu Ling Zhi). It is traditionally indicated for promoting blood circulation, removing blood stasis, and alleviating pain. In modern clinical research, it is being investigated by Longhua Hospital and the Shanghai University of Traditional Chinese Medicine for its potential therapeutic effects in primary biliary cholangitis (PBC), particularly when used in combination with Er-Zhi-Wan Pill and standard ursodeoxycholic acid (UDCA) therapy. The formula is hypothesized to address the blood stasis component of PBC pathology and provide anti-inflammatory and anti-fibrotic benefits.

Other names: Shi-Xiao-San PowderSudden Smile PowderShixiao SanShixiaosan

Beyond the preview

Go deeper on Shi-Xiao-San.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Shi-Xiao-San.

Explore the full profile