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Shift Bioscience unnamed RNAi program
- Development stage
- Preclinical
- Lead developer
- Shift Bioscience
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
Shift Bioscience's unnamed RNAi program is a preclinical therapeutic candidate designed to treat liver fibrosis by targeting a specific pro-aging gene. Utilizing small interfering RNA (siRNA) technology, the program aims to achieve knockdown of a target identified through the company's machine learning platform, which maps genes that drive the cellular aging process. While the initial focus is on liver fibrosis, Shift Bioscience intends to expand the application of this siRNA-mediated knockdown approach to other tissue types. The program is currently in the target validation and preclinical development stage.
- Other names
- Shift Bioscience siRNA programShift Bioscience liver fibrosis program
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