Drug intelligence / Profile preview

shigella conjugate vaccine

Development stage
Preclinical
Lead developer
Techinvention Lifecare
Modality
Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

This shigella conjugate vaccine is a preclinical-stage candidate developed by Techinvention Lifecare for the prevention of shigellosis. The vaccine utilizes a conjugation strategy, linking *Shigella* surface antigens—typically the O-specific polysaccharide (OSP) of the lipopolysaccharide—to a carrier protein. This approach is designed to overcome the poor immunogenicity of pure polysaccharides, particularly in infants and young children, by inducing a T-cell dependent immune response. The goal is to provide broad protection against the most prevalent *Shigella* serotypes responsible for severe diarrhea and dysentery globally.

Other names
Techinvention Shigella vaccine
02

Targets

S. flexneri 2a O-antigen (Shigella flexneri 2a O-antigen)

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