Drug intelligence / Profile preview

Shincort

Development stage
Unknown
Lead developer
Yung Shin Pharmaceutical Industry
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Intramuscular, Intraarticular
01

Overview

Triamcinolone acetonide is a synthetic glucocorticoid corticosteroid used for its potent anti-inflammatory and immunosuppressive effects. It acts by binding to the glucocorticoid receptor, inhibiting phospholipase A2 activity, and suppressing the formation of pro-inflammatory mediators such as prostaglandins and leukotrienes. This results in reduced inflammation, immune response modulation, and relief from symptoms associated with various allergic, inflammatory, autoimmune, and rheumatic conditions. Shincort is typically administered via intramuscular or intra-articular injection for indications including rheumatoid arthritis (RA), synovitis, allergic rhinitis, asthma, allergic dermatitis, pemphigus vulgaris, bursitis, and certain ophthalmic diseases[3][5]. The drug is not intended for intravenous use.

Brand names
Shincort
02

Targets

GR (Glucocorticoid receptor)

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